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Capital Health Summit

Shoulder replacement set out by someone who had one: how total, reverse, and partial differ, what the rotator cuff decides, the rehab that makes the result, and how long the joint holds.
Shoulder replacement, from the worn joint to the settled result.

Shoulder Replacement Anaesthesia: The General Anaesthetic and Interscalene Nerve Block

By Douglas Prentice  |  Medically reviewed by Mr Robert Kessler, FRCS (Tr & Orth)

Published April 11, 2026 · Last refreshedMay 11, 2026 · Last reviewed May 13, 2026

Key takeaways

  • A shoulder replacement is almost always done under a general anaesthetic, usually combined with a regional nerve block (an interscalene block) that numbs the arm and carries most of the pain relief for the first day.
  • The interscalene block is an injection of local anaesthetic around the nerves in the lower neck, placed with ultrasound guidance, and it is the standard regional technique for shoulder surgery because it cuts pain scores and opioid use afterwards.
  • Some centres offer the operation awake under the block alone, which avoids the sore throat, nausea and grogginess of a general anaesthetic, though it needs the right patient and enough breathing reserve.
  • The block leaves the whole arm heavy, warm and completely dead for the first day; the honest surprise is the rebound pain when it wears off, which is why pain relief is started before the numbness goes.
  • Common, mostly temporary block effects include a hoarse voice, a droopy eyelid, and one side of the diaphragm resting for a few hours; lasting nerve injury is rare, and the anaesthetist weighs all of this at your pre-assessment.

A shoulder replacement is almost always done under a general anaesthetic, so you are asleep for the operation, usually combined with a regional nerve block (an interscalene block) that numbs the whole arm and carries most of the pain relief for the first day.1 A few centres now offer the operation awake under the block alone, but for most primary replacements the general-plus-block combination is the standard arrangement.

When I had my reverse replacement I assumed anaesthesia meant one decision: asleep or not. It turned out to be two things working together, and the block was the part nobody had prepared me for. This is the plain version I wanted beforehand. If you want the wider picture of the day itself, read the shoulder replacement procedure; for the operation as a whole, start with the shoulder replacement guide.

What anaesthetic is used for a shoulder replacement?

The usual arrangement is a general anaesthetic combined with an interscalene nerve block: the general anaesthetic keeps you asleep and still for the roughly 1.5 to 2 hours a primary replacement takes, and the block numbs the arm so you wake with the shoulder already pain-free.1 The two are not rivals; pairing them lets the anaesthetist run a lighter general anaesthetic and hand you over to recovery with the pain already covered rather than chasing it afterwards.

The reason the block earns its place is measurable. Reviews of interscalene blocks for shoulder surgery report lower pain scores and less opioid use in the first day compared with a general anaesthetic on its own, which is why it has become the default regional technique for this operation2. My anaesthetist described it as doing the heavy lifting on pain while I slept through the surgery itself.

What is an interscalene nerve block?

An interscalene block is an injection of local anaesthetic placed around the brachial plexus, the bundle of nerves in the lower neck that carries all the sensation and movement of the arm, guided by ultrasound so the anaesthetist can watch the needle and the nerves on screen.3 Within about half an hour the shoulder and arm go numb, heavy and hard to move, which is exactly the point4.

A nerve block is not the same as being put to sleep: it switches off one region of the body while the rest of you carries on3. For the shoulder it is the gold-standard regional method precisely because that one region is the whole surgical field. It can be given as a single injection or, less commonly, through a fine catheter left in place to top the numbness up over a day or two.

Can you be awake for a shoulder replacement?

Yes, in some centres the operation can be done awake under the interscalene block alone with light sedation, so you feel no pain but are not put to sleep, and once the arm is numb enough the surgeon starts.4 The draw is avoiding the general anaesthetic altogether: no sore throat from a breathing tube, less nausea and grogginess afterwards, an earlier drink and meal, and sometimes an earlier trip home.

It is not the right choice for everyone, and it is a conversation to have rather than a box to tick. The anaesthetist weighs your breathing reserve, your general health, and whether you would genuinely rather be aware in theatre. Comparable studies in reverse replacements have found the block with sedation to be a safe and cost-effective way to run the operation in suitable patients5. If it appeals, it belongs on your list in questions to ask before a shoulder replacement.

What the block actually feels like

The strangest part of the whole operation for me was not the surgery but waking to an arm I could not feel at all: heavy, warm, and so completely dead that a nurse had to tell me it was mine before I believed her. It sat across my chest like a sandbag, and for the best part of a day it belonged to someone else.

Nobody had described that to me, and I want to say it plainly because it can be unnerving if it lands as a surprise. The heaviness is the block working, not a complication, and the sensation and movement come back gradually as it wears off. The instruction that mattered was to protect the numb arm and not let it hang or catch, because you cannot feel it warning you4. I have written the rest of those first strange hours in my shoulder replacement recovery.

The side effects and risks

Most effects of the block are temporary and expected: a hoarse voice, a droopy eyelid on the same side, the warm numb arm, and one half of the diaphragm resting for a few hours, which people with good lungs barely notice.4 The diaphragm point is the one that shapes the decision, because someone with poor breathing reserve feels it far more, which is part of why the anaesthetist reviews your chest before settling the plan2.

Lasting nerve injury from the block is rare, and the general anaesthetic carries its own familiar and mostly minor after-effects: a sore throat, nausea, and drowsiness, with serious complications uncommon4. Blood clots are rarer after shoulder surgery than after hip or knee surgery. None of this is unique to the anaesthetic, and it sits alongside the wider picture in shoulder replacement risks and complications.

When the block wears off, and the pain afterwards

A single-injection block typically keeps the arm numb and pain-free well into the first day, commonly around 12 to 24 hours, and then wears off, sometimes with a sharp rebound of pain as the sensation floods back.2 For me it arrived in the small hours, which is apparently the usual timing, and it was the one genuinely rough night of the recovery.

The ward manages this by starting your regular pain relief before the numbness goes rather than waiting for the pain to announce itself, so the tablets are already working as the block fades2. Where a longer stretch of numbness is wanted, a continuous catheter block can carry the relief further into the recovery5. Knowing the rebound is coming is half the battle, and the days that follow settle into a steadier rhythm.

Getting ready: the pre-assessment

Before the day, a pre-operative assessment checks that you are fit for the anaesthetic, because general health and fitness matter as much for the anaesthetic as for the surgery.1 It is the point where the plan is actually decided: general anaesthetic with a block, or, in the right centre and the right patient, an awake block with sedation.

Come to it with questions rather than assumptions. It is worth asking whether they use a nerve block routinely, whether an awake option is on the table for you, and what the plan is for pain relief when the block wears off, since the answers vary between anaesthetists and hospitals4. Those belong on the same list as the surgical ones you take to the consultation.

References

  1. Shoulder Joint Replacement, American Academy of Orthopaedic Surgeons (AAOS OrthoInfo).
  2. Recent updates on interscalene brachial plexus block for shoulder surgery, PMC (review).
  3. Nerve Blocks, Cleveland Clinic.
  4. Awake anaesthesia for shoulder surgery, South Tees Hospitals NHS Foundation Trust (NHS).
  5. Safety and Cost-Effectiveness of Interscalene Brachial Plexus Block With Sedation in Reverse Total Shoulder Replacement, PMC (clinical study).

Common questions

What anaesthetic is used for a shoulder replacement?

Almost always a general anaesthetic, so you are asleep, and very often a regional nerve block (an interscalene block) on top. The block numbs the shoulder and arm and gives most of the pain relief for the first day. Some centres can do the operation awake under the block alone, but the general-plus-block combination is the usual arrangement for a primary replacement.

What is an interscalene nerve block?

It is an injection of local anaesthetic placed around the brachial plexus, the bundle of nerves in the lower neck that supplies the arm, guided by ultrasound so the anaesthetist can see the nerves and the needle. Within about half an hour the shoulder and arm go numb and heavy. It is the standard regional technique for shoulder surgery and is done before you are anaesthetised or just after.

Can you be awake for a shoulder replacement?

In some centres, yes. The operation can be done under the interscalene block alone with light sedation, so you stay awake but feel no pain. The appeal is avoiding the sore throat, nausea and grogginess of a general anaesthetic and often getting home sooner. It suits a well-selected patient; the anaesthetist decides whether your breathing reserve and general health make it a good idea.

Does the interscalene block affect your breathing?

Usually a little, on one side, and briefly. The block commonly rests the nerve to half of the diaphragm for a few hours, so people with good lungs barely notice it, while those with poor breathing reserve can find it significant. This is one of the main reasons the anaesthetist reviews your chest and general fitness before choosing a general anaesthetic, an awake block, or a combination.

How long does the nerve block last, and what happens when it wears off?

A single injection typically keeps the arm numb and pain-free well into the first day, commonly around 12 to 24 hours, then wears off. The honest catch is rebound pain: the shoulder can hurt sharply as sensation returns, often overnight. The ward starts your regular pain relief before the block fades so you are not caught out, and some patients have a fine catheter left in for a continuous block.

What are the risks of the anaesthetic and the block?

Most block effects are temporary: a hoarse voice, a droopy eyelid, a warm numb arm, and one side of the diaphragm resting for a few hours. Lasting nerve injury is rare. The general anaesthetic carries its own common effects such as a sore throat, nausea and drowsiness, with serious complications uncommon. Blood clots are rarer after shoulder surgery than after lower-limb surgery.

Written by Douglas Prentice. Medically reviewed by Mr Robert Kessler, FRCS (Tr & Orth).

Our guides are written from personal experience and reviewed by a qualified clinician for accuracy. Read our editorial policy.

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